[technology opportunities: LIFE SCIENCES]

> ANKtide Chemotherapeutic Peptide for Metastatic Cancer

A  novel peptide (ANKtide) that is effective in reducing breast cancer tumours in vivo preclinical models. The peptide holds promise as a novel chemotherapeutic for metastatic cancers.

> Broad-Acting Anti-Alzheimer's compound- NH7211

Novel small chemical compounds capable of disrupting the three key misfolded proteins responsible for Alzheimer’s disease (AD) and other CNS disorders. 

> Canine Factor VIII Gene, Protein and Use
Technology providing methods useful during diagnosis of a canine Factor VIII deficiency-dependent bleeding disorder, and methods for treating a canine afflicted with such a disorder.

> Decellularized Adipose Tissue for Soft Tissue Augmentation

A detergent-free and collagenase-free method of processing adipose tissue that yields an intact extracellular matrix with significant architecture and volume, but that is devoid of cells.

> DETECTS - Software for Identifying Circulatory Emboli

Detection of Emboli using Trans-esophageal Echocardiography for Counting, Total volume, and Size estimation. This software tool accurately measures flow rates of emboli in the ascending aorta while simultaneously providing quantitative data on size, volume and count.

> Drug Delivery System

A suite of proprietary extended release drug delivery systems based on absorbable elastomers and injectable polymers.

> Follicular Lymphoma Predictive Assay

The Follicular Lymphoma Assay uses gene pairs identified from expression arrays of tissues from FL patients and can predict 5 year mortality with greater than 85% accuracy.

> Kinarm™ - Mechanical Linkage to Study Multi-Joint Movements
Robotic exoskeleton that can both sense and modify the mechanics of multi-joint movements. Researchers can use this device to examine a range of questions on motor coordination and learning. Development of a clinical assessment tool is underway.

> Methods of Treating a CNS Disorder Using N,N-Dichlorinated Amino Acids and Derivatives
Compounds and methods for the synthesis of chlorinated amino acids for treatment of central nervous system (CNS) disorders including epilepsy and Alzheimer's.

> Multi-Drug Resistant Protein (MRP)
Queen's University researchers Drs. Susan Cole and Roger Deeley were the first to clone the human Multi-drug Resistance Protein (MRP) following their 1992 discovery of the gene encoding Multidrug Resistance Proteins (MRP).

> Neuroprotective Agent for the Treatment of Ischemic Stroke

Researchers at the Centre for Addiction and Mental Health have developed a novel neuroprotective peptide agent capable of reducing the amount of ischemic brain injury.

> Patient-Specific Surgical Guide

patient-specific guide that employs a verification tool and adjustable instrument sleeves to alter, if necessary, the surgical approach provided by the guide.

> Prognostic Tool for Chronic Heart Failure

A novel ECG technology that predicts mortality with great accuracy, within 5 years, in chronic heart failure patients.  Currently there are no reliable or accurate tests to predict CHF mortality. 

> Reproductive Technology: Enhanced ICSI – Sperm Oocyte-Activating Factor 

Researchers at Queen's University and University of Missouri have identified PAWP (postacrosomal sheath WW domain binding protein, gene WBP2NL, also known as PT32) as an oocyte-activating factor that induces fertilization events including meiotic resumption, pronuclear formation, and egg cleavage. 

> SW-01 - A Novel Anti-Cancer Compound

A genericized drug compound, SW-01, specific for inhibiting the RET receptor tyrosine kinase.  SW-01 has powerful anti-cancer properties and is effective in reducing pancreatic cancer tumours in a number of in vivo preclinical models. This compound has the potential for treating a number of cancer types involving RET.

> Spinal Cord Function Imaging System

A novel and innovative thermal stimulation and analysis system that, in combination with MRI, enables researchers and clinicians to view images of the spinal cord that depict where the cord is working to process a sensation or impulse to move.